The Pathobiology and Extracellular Vesicles research group aims to unravel the interplay of innate, adaptive, and epigenetic contribution to pathobiological processes, leading to the identification of novel molecular targets and therapies to improve human health during their lifespan and to expand our understanding of the One Health concept.
By using interdisciplinary approaches comprised of multi-omics (genomics, transcriptomics, proteomics, metabolomics), liquid biopsy tools (extracellular vesicle (EV) fingerprinting), molecular and protein modelling (post-translational modifications, molecular docking), we are developing tools for disease fingerprinting and to aid drug-discovery.
We work and collaborate across multiple disciplines locally, nationally, and internationally using in silico, in vitro and in vivo approaches of human and comparative models.
The multidisciplinary group is composed of experts in pathobiology, developmental biology, immunology, chronic and neurodegenerative disease, regenerative medicine, vascular biology, infectious disease, pharmacology and drug-development, bioinformatics, and molecular modelling.