2024
- O'Donovan SD, Rundle M, Thomas EL, Bell JD, Frost G, Jacobs DM, Wanders A, de Vries R, Mariman ECM, van Baak MA, Sterkman L, Nieuwdorp M, Groen AK, Arts ICW, van Riel NAW, Afman LA. Quantifying the effect of nutritional interventions on metabolic resilience using personalized computational models. iScience. 2024 Feb 29;27(4):109362. doi: 10.1016/j.isci.2024.109362
- Smith HE, Mackenzie AM, Seddon C, Mould R, Kalampouka I, Malakar P, Needham SR, Beis K, Bell JD, Nunn A, Botchway SW. The use of NADH anisotropy to investigate mitochondrial cristae alignment. Sci Rep. 2024 Mar 12;14(1):5980. doi: 10.1038/s41598-024-55780-5. PMID: 38472304; PMCID: PMC10933486
- Mould RR, Mackenzie AM, Kalampouka I, Nunn AVW, Thomas EL, Bell JD, Botchway SW. Ultra weak photon emission-a brief review. Front Physiol. 2024 Feb 14;15:1348915. doi: 10.3389/fphys.2024.1348915
- Thanaj M, Basty N, Whitcher B, Sorokin E, Liu Y, Srinivasan R, Cule M, Thomas EL, and Bell JD. Precision MRI phenotyping of muscle volume and quality at a population scale. Front. Physiol., 15, 1288657 (2024). https://doi.org/10.3389/fphys.2024.1288657
- Thanaj M, Basty N, Cule M, Sorokin EP, Whitcher B, Bell JD and Thomas EL. Liver shape analysis using statistical parametric maps at population scale. BMC Med Imaging 24, 15 (2024). https://doi.org/10.1186/s12880-023-01149-5
2023
- Thanaj M, Basty N, Cule M, Sorokin EP, Whitcher B, Srinivasan R, Lennon R, Bell JD and Thomas EL. Kidney shape statistical analysis: associations with disease and anthropometric factors. BMC Nephrol 24, 362 (2023). https://doi.org/10.1186/s12882-023-03407-8
- Mould RR, Kalampouka I, Thomas EL, Guy GW, Nunn AVW, Bell JD. Non-chemical Signalling Between Mitochondria. Front. Physiol. Sec. Biophysics. Volume 14 - 2023 | doi: 10.3389/fphys.2023.1268075
- Corpas M, de Mendoza C, Moreno-Torres V, Pintos I, Seoane P, Perkins JR, Ranea JAG, Fatumo S, Korcsmaros T, Martín-Villa JM, Barreiro P, Corral O, Soriano V. Genetic signature detected in T cell receptors from patients with severe COVID-19. iScience. 2023 Aug 25;26(10):107735. doi: 10.1016/j.isci.2023.107735
- Rundle M, Fiamoncini J, Thomas EL, Wopereis S, Afman LA, Brennan L, Drevon CA, Gundersen TE, Daniel H, Perez IG, Posma JM, Ivanova DG, Bell JD, van Ommen B, Frost G. Diet-induced Weight Loss and Phenotypic Flexibility Among Healthy Overweight Adults: A Randomized Trial. Am J Clin Nutr. 2023 Sep;118(3):591-604. doi: 10.1016/j.ajcnut.2023.07.002
- Skantharajah N, Baichoo S, Boughtwood TF, Casas-Silva E, Chandrasekharan S, Dave SM, Fakhro KA, Falcon de Vargas AB, Gayle SS, Gupta VK, Hendricks-Sturrup R, Hobb AE, Li S, Llamas B, Lopez-Correa C, Machirori M, Melendez-Zajgla J, Millner MA, Page AJH, Paglione LD, Raven-Adams MC, Smith L, Thomas EM, Kumuthini J, Corpas M. Equity, diversity, and inclusion at the Global Alliance for Genomics and Health. Cell Genom. 2023 Aug 24;3(10):100386. doi: 10.1016/j.xgen.2023.100386
- Kamiza AB, Touré SM, Zhou F, Soremekun O, Cissé C, Wélé M, Touré AM, Nashiru O, Corpas M, Nyirenda M, Crampin A, Shaffer J, Doumbia S, Zeggini E, Morris AP, Asimit JL, Chikowore T, Fatumo S. Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry. Nat Commun. 2023 Sep 5;14(1):5403. doi: 10.1038/s41467-023-41271-0
- Corpas M, Fatumo S. Generalisation of genomic findings and applications of polygenic risk scores. BMC Med Genomics. 2023 Jul 28;16(1):175. doi: 10.1186/s12920-023-01615-7. PMID: 37507694; PMCID: PMC10386601
- Corpas M, Siddiqui MK, Soremekun O, Mathur R, Gill D, Fatumo S. Addressing Ancestry and Sex Bias in Pharmacogenomics. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:53-64. doi: 10.1146/annurev-pharmtox-030823-111731. Epub 2023 Jul 14. PMID: 37450899.
Dar NJ, Bhat SA, Rehman MU, Booker A. Editorial: Investigating the molecular targets and therapeutic potential of Withania somnifera (Ashwagandha) in various pathophysiological conditions. Front Pharmacol. 2023 May 2;14:1187334. doi: 10.3389/fphar.2023.1187334 - Nunn AVW, Guy GW, Bell JD. Informing the Cannabis Conjecture: From Life's Beginnings to Mitochondria, Membranes and the Electrome-A Review. Int J Mol Sci. 2023 Aug 22;24(17):13070. doi: 10.3390/ijms241713070
- Aguida B, Chabi MM, Baouz S, Mould R, Bell JD, Pooam M, André S, Archambault D, Ahmad M, Jourdan N. Near-Infrared Light Exposure Triggers ROS to Downregulate Inflammatory Cytokines Induced by SARS-CoV-2 Spike Protein in Human Cell Culture. Antioxidants (Basel). 2023 Oct 2;12(10):1824. doi: 10.3390/antiox12101824
- Mortoglou M, Miralles F, Mould RR, Sengupta D, Uysal-Onganer P. Inhibiting CDK4/6 in pancreatic ductal adenocarcinoma via microRNA-21. Eur J Cell Biol. 2023 Jun;102(2):151318. doi: 10.1016/j.ejcb.2023.151318
- Basty N, Sorokin EP, Thanaj M, Srinivasan R, Whitcher B, Bell JD, Cule M, Thomas EL. Abdominal imaging associates body composition with COVID-19 severity. PLoS One. 2023 Apr 13;18(4):e0283506. doi: 10.1371/journal.pone.0283506.
Basty N, Thanaj M, Cule M, Sorokin EP, Liu Y, Thomas EL, Bell JD and Whitcher B. Artifact-free fat-water separation in Dixon MRI using deep learning. J Big Data 10, 4 (2023). - Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, Brorsson C, Mazzoni G, Niu L, Biel JH, Brasas V, Webel H, Benros ME, Pedersen AG, Chmura PJ, Jacobsen UP, Mari A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Hong MG, Musholt PB, De Masi F, Vogt J, Pedersen HK, Gudmundsdottir V, Jones A, Kennedy G, Bell J, Thomas EL, Frost G, Thomsen H, Hansen E, Hansen TH, Vestergaard H, Muilwijk M, Blom MT, 't Hart LM, Pattou F, Raverdy V, Brage S, Kokkola T, Heggie A, McEvoy D, Mourby M, Kaye J, Hattersley A, McDonald T, Ridderstråle M, Walker M, Forgie I, Giordano GN, Pavo I, Ruetten H, Pedersen O, Hansen T, Dermitzakis E, Franks PW, Schwenk JM, Adamski J, McCarthy MI, Pearson E, Banasik K, Rasmussen S, Brunak S; IMI DIRECT Consortium. Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models. Nature Biotechnology, 2023. Epub ahead of print. PMID: 36593394.
2022
- Ichim MC, Scotti F, Booker A. Quality evaluation of commercial herbal products using chemical methods. Critical Reviews in Food Science and Nutrition, 2022. 31:1-21. Epub ahead of print. PMID: 36315039.
- O’Donovan SD, Balázs E, Jacobs DM, Wanders AJ, Thomas EL, Bell JD, Rundle M, Frost G, Arts ICW, Afman LA, Riel NAW. Quantifying the contribution of triglycerides to metabolic resilience through the Mixed Meal Model. iScience 2022. 3;25(11):105206.
- Nunn AVW, Guy GW, Brysch W, Bell JD. Understanding Long COVID; Mitochondrial Health and Adaptation-Old Pathways, New Problems. Biomedicines, 2022. 2;10(12):3113.
- Mould RR, Thomas EL, Guy G, Nunn AVW, and Bell JD. Cell-Cell Death Communication by Signals Passing Through Non-Aqueous Environments: A Reply. Results in Chemistry, 2022, 100538.
- Asaturyan HA, Basty N, Thanaj M, Whitcher B, Thomas EL, and Bell JD. Improving the accuracy of fatty liver index to reflect liver fat content with predictive regression modelling. PLoS ONE 17(9): e0273171.
- Cresswell E, Karpe F and Basty N. Neck fat estimation from DXA using convolutional neural networks. Medical Image Understanding and Analysis: 26th Annual Conference, MIUA 2022, Cambridge, UK, July 27–29, 2022, Proceedings Jul 2022 Pages 3–12.
- Nunn AVW, Guy GW, and Bell JD. Bioelectric Fields at the Beginnings of Life. Bioelectricity. July 8, 2022 ahead of print.
- Fiamoncini J, Donado-Pestana CM, Duarte GBS, Rundle M, Thomas EL, Kiselova-Kaneva Y, Gundersen TE, Bunzel D, Trezzi JP, Kulling SE, Hiller K, Sonntag D, Ivanova D, Brennan L, Wopereis S, van Ommen B, Frost G, Bell JD, Drevon CA and Daniel H. Plasma metabolic signatures of healthy overweight subjects challenged with an oral glucose tolerance test. Frontiers in Nutrition: Nutrition and Metabolism. 2022 9:898782.
- Ozairi DEA, Awadi RA, El Samad A, Taghadom E, Al-Kandari J, Abdul-Ghani M, Oliver N, Whitcher B, Guess N. A Randomised Crossover Trial: Exploring the Dose-Response effect Of Carbohydrate restriction on glycaemia in people with well-controlled type 2 diabetes (D-ROC2): Summary. J Hum Nutr Diet. 2022 May 12.
- Sorokin E, Basty N, Whitcher B, Liu Y, Bell JD, Cohen RL, Cule M and Thomas EL Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis. American Journal of Human Genetics. 2022 May 10:S0002-9297(22)00161-6.
- Gu J, Scotti F, Reich E, Kirchhof R, Booker A, and Heinrich M. Chrysanthemum species used as food and medicine: Understanding quality differences on the global market. South African Journal of Botany 2022; 148: 123-134.
- Sheridan DA, Shawa IT, Thomas EL, Felmlee DJ, Bridge SH, Neely D, Cobbold JF, Holmes E, Bassendine MF, Taylor-Robinson SD. Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis. Sci Rep. 2022 Apr 1;12(1):5562.
- Osimo E, Brugger S, Thomas EL, and Howes O. A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia. Schizophr 2022;8: 24
- Whitcher B, Thanaj M, Cule M, Liu Y, Basty N, Sorokin EP, Bell JD, Thomas EL. Precision MRI Phenotyping Enables Detection of Small Changes in Body Composition for Longitudinal Cohorts. Scientific Reports 2022 in press.
- Nunn AVW, Guy GW and Bell JD. Thermodynamics and Inflammation: Insights into Quantum Biology and Ageing. Quantum Rep. 2022, 4(1), 47-74.
- Martin S, Tyrrell J, Thomas EL, Bown MJ, Wood AR, Beaumont RN, Tsoi LC, Stuart PE, Elder JT, Law P, Houlston R, Kabrhel C, Papadimitriou N, Gunter MJ, Bull CJ, Bell JA, Vincent EE, Sattar N, Dunlop MG, Tomlinson IPM, Bell JD, Frayling TM, Yaghootkar H. Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation. eLife 2022;11:e72452.
- Wesolowska-Andersen A, Brorsson CA, Bizzotto R, Mari A, Tura A, Koivula R, Mahajan A, Viñuela A, Fernandez-Tajes J, Sharma S, Haid M, Prehn C, Artati A, Hong M-G, Musholt PB, Kurbasic A, Masi F, Tsirigos K, Pedersen H, Gudmundsdottir V, Thomas C, Banasik K, Jennison C, Jones A, Kennedy G, Bell JD, Thomas EL, Frost G, et al., Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study. Cell Reports Medicine 2022, 3, 100477.
- Martin S, Sorokin EP, Thomas EL, Sattar N, Cule M, Bell JD, Yaghootkar H. Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study. Diabetes Care. 2021 Dec 22:dc211262. Epub ahead of print.
2021
- Osimo EF, Sweeney M, de Marvao A, Berry A, Statton B, Perry BI, Pillinger T, Whitehurst T, Cook SA, O’Regan DP, Thomas EL and Howes OD. Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case–control study. Transl Psychiatry 11, 614 (2021).
- Nunn AVW, Guy GW, Botchway SW, Bell JD. SARS-CoV-2 and EBV; the cost of a second mitochondrial "whammy"? Immun Ageing. 2021 Oct 30;18(1):40.
- Booker A. Editorial: Overcoming the Challenges of Herbal Adulteration in a Globalized World. Front Pharmacol. 2021 Nov 22;12:793616.
- Scotti F, Mou L, Huang C, Booker A, Weckerle C, Maake C, Heinrich M. Treating Chronic Wounds Using Photoactive Metabolites: Data Mining the Chinese Pharmacopoeia for Potential Lead Species. Planta Med. 2021 Nov;87(14):1206-1218. Epub 2021 Sep 15. PMID: 34528222; PMCID: PMC8585569.
- Thanaj M, Basty N, Liu Y, Cule M, Sorokin EP, Thomas EL, Bell JD and Whitcher B. (2021) Mass Univariate Regression Analysis for Three-Dimensional Liver Image-Derived Phenotypes. In: Papież B.W., Yaqub M., Jiao J., Namburete A.I.L., Noble J.A. (eds) Medical Image Understanding and Analysis. MIUA 2021. Lecture Notes in Computer Science, vol 12722. Springer, Cham.
- Villarini B, Asaturyan H, Kurugol S, Afacan O, Bell JD and Thomas EL. 3D Deep Learning for Anatomical Structure Segmentation in Multiple Imaging Modalities. 34th IEEE CBMS International Symposium on Computer-Based Medical Systems 2021 166-171.
- Liu Y, Basty N, Whitcher B, Bell JD, Sorokin EP, van Bruggen N, Thomas EL and Cule M. Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Elife. 2021 Jun 15;10:e65554.
- Martin S, Cule M, Basty N, Tyrrell J, Beaumont RN, Wood AR, Frayling TM, Sorokin E, Whitcher B, Liu Y, Bell JD, Thomas EL, Yaghootkar H. Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Diabetes. 2021 Aug;70(8):1843-1856.
- Mould RR, Botchway SW, Parkinson JRC, Thomas EL, Guy GW, Bell JD and Nunn AV. Cannabidiol modulates mitochondrial redox and dynamics in MCF7 cancer cells: a study using fluorescence lifetime imaging microscopy of NAD (P) H. Frontiers in Molecular Biosciences. 2021, 8, 132.
- Ichim MC, Booker A. Chemical Authentication of Botanical Ingredients: A Review of Commercial Herbal Products. Front. Pharmacol., 15 April 2021 Front Pharmacol. 2021 Apr 15;12:666850. eCollection 2021.
- Sahuri Arisoylu M, Mould RR, Shinjyo N, Bligh SW, Nunn AV, Guy GW, Thomas EL and Bell JD. Acetate induces growth arrest in colon cancer cells through modulation of mitochondrial function Frontiers in Nutrition. 2021, 8, 150.
- Woodley Sb, Mould RR, Sahuri Arisoylu M, Kalampouka I, Booker A, JD Bell. Mitochondrial Function as a Potential Tool for Assessing Function, Quality and Adulteration in Medicinal Herbal Teas. Frontiers in Pharmacology Front. Pharmacol., 26 April 2021.
- Bizzotto R, Jennison C, Jones AG, Kurbasic A, Tura A, Kennedy G, Bell JD, Thomas EL, Frost G, Eriksen R, Koivula RW, Brage S, Kaye J, Hattersley AT, Heggie A, McEvoy D, 't Hart LM, Beulens JW, Elders P, Musholt PB, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Lundgaard AT, Thomsen HS, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis E, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, Franks PW, Walker M, Pearson ER, Mari A; IMI DIRECT consortium. Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study. Diabetes Care. 2021 Feb;44(2):511-518.
- Heinrich M, Jiang H, Scotti F, Booker A, Walt H, Weckerle C, Maake C. Medicinal plants from the Himalayan region as potential novel antimicrobial and anti-inflammatory skin treatments. Journal of Pharmacy and Pharmacologyl. 2021 Apr 22:rgab039.
2020
- Nunn AVW, Guy GW, Brysch W, Botchway SW, Frasch W, Calabrese EJ, Bell JD. SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing. Immunity & Ageing 2020; 17:33.
- Fitzpatrick JA, Basty N, Cule M, Liu Y, Bell JD, Thomas EL, Whitcher B. Large-scale analysis of iliopsoas muscle volumes in the UK Biobank. Sci Rep. 2020; 10:20215.
- Alenaini A, Parkinson JRC, McCarthy JP, Goldstone AP, Wilman HR, Banerjee R, Yaghootkar H, Bell JD and Thomas EL. Ethnic differences in body fat deposition and liver fat content in two UK based cohorts. Obesity 2020 28:2142-2152.
- Machann J, Stefan N, Wagner R, Fritsche A, Bell JD, Whitcher B, Häring H-U, Birkenfeld AL, Nikolaou K, Schick F, Thomas EL. Normalized Indices Derived from Visceral Adipose Mass Assessed by Magnetic Resonance Imaging and Their Correlation with Markers for Insulin Resistance and Prediabetes. Nutrients. 2020;12(7):E2064.
- Littlejohns TJ, Holliday J, Gibson LM, Garratt S, Oesingmann N, Alfaro-Almagro F, Bell JD, Boultwood C, Collins R, Conroy MC, Crabtree N, Doherty N, Frangi AF, Harvey NC, Leeson P, Miller KL, Neubauer S, Petersen SE, Sellors J, Sheard S, … Allen NE. The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions. Nat Commun. 2020;11(1):2624.
- Eriksen R, Perez IG, Posma JM, Haid M, Sharma S, Thomas EL, Koivula RW, Bizzotto R, Mari A, Giordano GN, Pavo I, Schwenk J, De Masi F, Tsirigos K, Brunak S, Vinuela A, Mahajan A, McDonald TJ, Kokkola T, Teare HJA, Hansen TH, Fernandez J, Jones, A, Jennison C, Walker M, McCarthy M, Pedersen O, Reutten H, Forgie I, Bell JD, Pearson E, Franks PW, Adamski J, Holmes E and Frost GS. Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI Direct study. EBioMedicine. 2020; 58:102932.
- Vincent EE, Yaghootkar H. Using genetics to decipher the link between type 2 diabetes and cancer: shared aetiology or downstream consequence?. Diabetologia. 2020;63(9):1706-1717.
- Atabaki-Pasdar N, Ohlsson M, Viñuela A, Frau F, Pomares-Millan H, Haid M, Jones AG, Thomas EL, Koivula RW, Kurbasic A, Mutie PM, Fitipaldi H, Fernandez J, Dawed AY, Giordano GN, Forgie IM, McDonald TJ, Rutters F, Cederberg H, Chabanova E,... Bell JD,… Franks PW. Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts. PLoS Med. 2020;17(6):e1003149.
- Dikariyanto V, Smith L, Francis L, Robertson M, Kusaslan E, O'Callaghan-Latham M, Palanche C, D'Annibale M, Christodoulou D, Basty N, Whitcher B, Shuaib H, Charles-Edwards G, Chowienczyk PJ, Ellis PR, Berry SEE, Hall WL. Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial. Am J Clin Nutr. 2020 Jun 1;111(6):1178-1189.
- Aldraimli M, Soria D, Parkinson J, Thomas EL, Bell JD, Dwek MV, Chaussalet TJ. Machine learning prediction of susceptibility to visceral fat associated diseases. Health Technol. 2020;10, 925–944.
- Casanova F, Wood AR, Yaghootkar H, Beaumont RN, Jones SE, Gooding KM, Aizawa K, Strain WD, Hattersley AT, Khan F, Shore AC, Frayling TM, Tyrrell J. A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function. Diabetes. 2020 May;69(5):1072-1082.
- Whyte, F Shojaee-Moradie, SE Sharaf, DJ Cuthbertson, GJ Kemp, M Barrett, NC Jackson, RA Herring, J Wright, EL Thomas, J Bell, AM Umpleby HDL-apoA-I kinetics in response to 16 wk of exercise training in men with nonalcoholic fatty liver disease, Am J Physiol Endocrinol Metab. 2020;318(6):E839-E847.
- Yaghootkar H, Whitcher B, Bell JD, Thomas EL. Ethnic differences in adiposity and diabetes risk - insights from genetic studies. J Intern Med. 2020.
- Basty N, Liu Y, Cule M, Thomas EL, Bell JD, Whitcher B. Automated Measurement of Pancreatic Fat and Iron Concentration Using Multi-Echo and T1-Weighted MRI Data. 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), 345-348.
- Parisinos CA, Wilman HR, Thomas EL, Kelly M, Nicholls RC, McGonigle J, Neubauer S, Hingorani AD, Patel RS, Hemingway H, Bell JD, Banerjee R, Yaghootkar H. Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. J Hepatol. 2020;S0168-8278(20)30194-X.
- Parkinson JRC, Emsley R, Adkins JLT, Longford N, Ozanne SE, Holmes E, Modi N. Clinical and molecular evidence of accelerated ageing following very preterm birth. Pediatr Res. 2020 May;87(6):1005-1010.
- Nunn AVW, Guy GW, Botchway SW, Bell JD. From sunscreens to medicines: Can a dissipation hypothesis explain the beneficial aspects of many plant compounds? Phytother Res. 2020.
- Koivula RW, Atabaki-Pasdar N, Giordano GN, White T, Adamski J, Bell JD, Beulens J, Brage S, Brunak S, De Masi F, Dermitzakis ET, Forgie IM, Frost G, Hansen T, Hansen TH, Hattersley A, Kokkola T, Kurbasic A, Laakso M, Mari A, McDonald TJ, Pedersen O, Rutters F, Schwenk JM, Teare HJA, Thomas EL, Vinuela A, Mahajan A, McCarthy MI, Ruetten H, Walker M, Pearson E, Pavo I, Franks PW; IMI DIRECT Consortium.. The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study. Diabetologia. 2020;63(4):744-756.
- Shinjyo N, Parkinson J, Bell J, Katsuno T, Bligh A. Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review. J Integr Med. 2020 Mar;18(2):125-151.
- Fitzgerald M, Heinrich M, Booker A. Medicinal Plant Analysis: A Historical and Regional Discussion of Emergent Complex Techniques. Front Pharmacol. 2020 Jan 9;10:1480.
2019
- Asaturyan H, Thomas EL, Bell JD, Villarini B. A Framework for Automatic Morphological Feature Extraction and Analysis of Abdominal Organs in MRI Volumes. J Med Syst. 2019;43(12):334.
- Aldraimli M, Soria D, Parkinson J, Whitcher B, Thomas EL, Bell JD, Chaussalet TJ and Dwek MV. Machine Learning Classification of Females Susceptibility to Visceral Fat Associated Diseases. In: Henriques J., Neves N., de Carvalho P. (eds) XV Mediterranean Conference on Medical and Biological Engineering and Computing - MEDICON 2019. MEDICON 2019. IFMBE Proceedings, vol 76. Springer, Cham
- Mani BK, Puzziferri N, He Z, Rodriguez JA, Osborne-Lawrence S, Metzger NP, Chhina N, Gaylinn BD, Thorner MO, Thomas EL, Bell JD, Williams KW, Goldstone AP and Zigman JM. LEAP2 changes with body mass and food intake in humans and mice. J Clin Invest. 2019;129(9):3909-3923.
- Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S, Mahajan A, Hingorani AD, Patel RS, Hemingway H, Franks PW, Bell JD, Banerjee R and Yaghootkar H. Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration. Journal of Hepatology. 2019; 71(3): 594-602.
- Frommenwiler DA, Booker A, Vila R, Heinrich M, Reich E, Cañigueral S. Comprehensive HPTLC fingerprinting as a tool for a simplified analysis of purity of ginkgo products. J Ethnopharmacol. 2019;243:112084.
- Koivula R, Forgie I, Kurbasic A, Viñuela A, Heggie A, Giordano G, Hansen T, Koopman A, Rutters F, Siloaho M, Kristine KH, Brage S, Brorsson CA, Dawed AY, De Masi F, Groves CJ, Kokkola T, Mahajan A, Perry MH, Rauh SP, Ridderstråle M, Teare HJA, Thomas EL, Tura A, Vestergaard H, White T, Adamski J, Bell JD, Beulens J, Brunak S, Dermitzakis ET, Froguel P, Frost G, Gupta R, Hansen T, Hattersley A, Jablonka B, Kaye J, Laakso M, McDonald TJ, Pedersen O, Schwenk JM, Pavo I, Mari A, McCarthy MI, Ruetten H, Walker M, Pearson E and Franks PW, for the IMI DIRECT Consortium. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium. Diabetologia 2019; 2019, 62(9): 1601-1615.
- Ji Y, Yiorkas AM, Frau F, Mook-Kanamori D, Staiger H, Thomas EL, Atabaki-Pasdar N, Campbell A, Tyrrell J, Jones SE, Beaumont RN, Wood AR, Tuke MA, Ruth KS, Mahajan A, Murray A, Freathy RM, Weedon MN, Hattersley AT, Hayward C, Machann J, Häring H-U, Franks P, de Mutsert R, Pearson E, Stefan N, Frayling TM, Allebrandt KV, Bell JD, Blakemore AI, Yaghootkar H. Genome-wide and abdominal MRI-imaging data provides evidence that a genetically determined favourable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease and hypertension. Diabetes 2019; 68(1): 207-219.
- Kosgodage US, Matewele P, Awamaria B, Kraev I, Warde P, Mastroianni G, Nunn AV, Guy GW, Bell JD, Inal JM, Lange S. Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles. Front Cell Infect Microbiol. 2019;9:324.
- Evangelou E, Gao H, Chu C,... Bell JD… et al. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nat Hum Behav. 2019;3(9):950-961.
- So PW, Ekonomou A, Galley K, Brody L, Sahuri-Arisoylu M, Rattray I, Cash D, Bell JD. Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke. Int J Nanomedicine. 2019;14:1979-1991. 65.
- Chatzinasiou L, Booker A, MacLennan E, Mackonochie M and Heinrich M. Turmeric (Curcuma longa L.) products: What quality differences exist? Journal of Herbal Medicine. 2019; 17-18:100281.
- Mojtahed A, Kelly CJ, Herlihy AH, Kin S, Wilman HR, McKay A, Kelly M, Milanesi M, Neubauer S, Thomas EL, Bell JD, Banerjee R, Harisinghani M. Reference range of liver corrected T1 values in a population at low risk for fatty liver disease - a UK Biobank sub-study, with an appendix of interesting cases. Abdom. Radiol. (NY). 2019 Jan;44(1):72-84.
- Scotti F, Lobel K, Booker A, et al. St. John's Wort (Hypericum perforatum) Products - How Variable Is the Primary Material? Frontiers In Plant Science 2019; 9: 1973.
- Chambers ES, Byrne CS, Rugyendo A, Morrison DJ, Preston T, Tedford MC, Bell JD, Thomas EL, Akbar AN, Riddell NE, Sharma R, Thursz MR, Manousou P and Frost G. The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease. Diabetes, Obes. Metab. 2019; 21(2): 372-376.
- Kosgodage US, Uysal-Onganer P, MacLatchy A, Mould R, Nunn AV, Guy GW, Kraev I, Chatterton NP, Thomas EL, Inal JM, Bell JD, Lange S. Cannabidiol affects Extracellular Vesicle release, miR21 and miR126, and reduces Prohibitin Protein in Glioblastoma Multiforme Cells. Transl Oncol. 2019; 12(3): 513-522.
- Agapouda A, Booker A, Kiss T et al. Quality control of Hypericum perforatum L. Analytical challenges and recent progress J. Pharm and Pharmacol. 2019; 71(1): 15-37.
- Linge J, Whitcher B, Borga M, Dahlqvist Leinhard O. Sub-phenotyping Metabolic Disorders Using Body Composition: An Individualized, Nonparametric Approach Utilizing Large Data Sets. Obesity (Silver Spring). 2019;27(7):1190-1199.
Publications prior to 2019
- McKay A, Wilman HR, Dennis A, Kelly M, Gyngell ML, Neubauer S, Bell JD, Banerjee R and Thomas EL. Measurement of liver iron by magnetic resonance imaging in the UK Biobank population. PLOS One 2018 Dec 21;13(12):e0209340.
- Mole DJ, Fallowfield JA, Kendall TJ, Welsh F, Semple SI, Bachtiar V, Kelly M, Wigmore SJ, James Garden O, Wilman HR, Banerjee R, Rees M, Brady M. BMC Cancer. Study protocol: HepaT1ca - an observational clinical cohort study to quantify liver health in surgical candidates for liver malignancies. 2018 Sep 12;18(1):890.
- Buckley A, Thomas EL, Lessan N, Trovato FM, Trovato GM and Taylor-Robinson SD. Non-alcoholic fatty liver disease: relationship with cardiovascular risk markers and clinical endpoints. Diabetes Res. Clin. Pract. 2018; 144: 144–154.
- Kosgodage US, Uysal-Onganer P, MacLatchy A, Mould R, Nunn AV, Guy GW, Kraev I, Chatterton NP, Thomas EL, Inal JM, Bell JD, Lange S. Cannabidiol affects Extracellular Vesicle release, miR21 and miR126, and reduces Prohibitin Protein in Glioblastoma Multiforme Cells. Transl Oncol. 2018 Dec 28;12(3):513–522.
- Chambers ES, Byrne CS, Rugyendo A, Morrison DJ, Preston T, Tedford MC, Bell JD, Thomas EL, Akbar AN, Riddell NE, Sharma R, Thursz MR, Manousou P and Frost G. The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease. Diabetes, Obes. Metab. Aug 2018. In Press.
- Buckley A, Thomas EL, Lessan N, Trovato FM, Trovato GM and Taylor-Robinson SD. Non-alcoholic fatty liver disease: relationship with cardiovascular risk markers and clinical endpoints. Diabetes Res. Clin. Pract. 2018; 144: 144–154.
- Kosgodage US, Mould R, Henley AB, Nunn AV, Guy GW, Thomas EL, Inal JM, Bell JD, Lange S. Cannabidiol (CBD) is a novel inhibitor for exosome and microvesicle (EMV) release in cancer. Front. Pharmacol. 2018; 9: 889.
- Linge J, Borger M, West J, Tuthill T, Miller MR, Dumitriu A, Thomas EL, Romu T, Tunón P, Bell JD, Leinhard OD. Body composition profiling in the UK Biobank imaging study. Obesity (Silver Spring). 2018; 26(11): 1785–1795.
- Borga M, West J, Bell JD, Harvey NC, Romu T, Heymsfield SB, Dahlqvist Leinhard O. Advanced body composition assessment: from body mass index to body composition profiling. J Investig Med. 2018; 66(5):1–9.
- Fiamoncini J, Rundle M, Gibbons H, Thomas EL, Geillinger-Kästle K, Bunzel D, Trezzi JP, Kiselova-Kaneva Y, Wopereis S, Wahrheit J, Kulling SE, Hiller K, Sonntag D, Ivanova D, van Ommen B, Frost G, Brennan L, Bell J, Daniel H. Plasma metabolome analysis identifies distinct human metabotypes in the postprandial state with different susceptibility to weight loss-mediated metabolic improvements. FASEB J. 2018; 32(10): 5447–5458
- Shafique M, Russell S, Murdoch S, Bell JD, Guess N. Dietary intake in people consuming a low-carbohydrate diet in the UK Biobank. J Hum Nutr Diet. 2018; 31(2): 228–238
- Cobbold JFL, Atkinson S, Marchesi JR, Smith A, Wai SN, Stove J, Shojaee-Moradie F, Jackson N, Umpleby AM, Fitzpatrick J, Thomas EL, Bell JD, Holmes E, Taylor-Robinson SD, Goldin RD, Yee MS, Anstee QM, Thursz MR. Rifaximin in non-alcoholic steatohepatitis: an open-label pilot study. Hepatol. Res. 2018; 48(1): 69–77.
- Umpleby AM, Shojaee-Moradie F, Fielding B, Li X, Marino A, Alsini N, Isherwood C, Jackson N, Ahmad A, Stolinski M, Lovegrove JA, Johnsen S, Mendis A, Wright J, Wilinska ME, Hovorka R, Bell JD, Thomas EL, Frost GS, Griffin BA. Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets. Clin. Sci. 2017; 131(21): 2561–2573.
- Brody LP, Sahuri Arisoylu M, Parkinson JR, Parkes HG, So PW, Hajji N, Thomas EL, Frost GS, Miller AD and Bell JD. Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects. Int. J. Nanomed. 2017; 12: 6677–6685.
- Villarini B, Asaturyan H, Thomas EL, Mould R, Bell JD. A framework for morphological feature extraction of organs from MR images for detection and classification of abnormalities. Proceedings of the 2017 IEEE 30th International Symposium on Computer-Based Medical Systems, CBMS 2017, Thessaloniki, Greece, 22-24 June 2017. 666–671.
- Wilman HR, Kelly M, Garratt S, Matthews PM, Milanesi M, Herlihy A, Gyngell M, Neubauer S, Bell JD, Banerjee R, Thomas EL. Characterisation of liver fat in the UK Biobank cohort. PLoS One. 2017; 12(2): e0172921.
- Shao A, Drewnowski A, Willcox DC, Krämer L, Lausted C, Eggersdorfer M, Mathers J, Bell JD, Randolph RK, Witkamp R, Griffiths JC. Optimal nutrition and the ever-changing dietary landscape: a conference report. Eur J Nutr. 2017; 56(Suppl 1): 1–21
- Fitzpatrick J, Chambers E, Parkinson JRC, Mould R, Frost G, Bell JD, Thomas EL. Psoas major cross sectional area: a potential marker of cardiorespiratory fitness. Int. J. Clin. Experiment. Physiol. 2017; 4(1): 15–20.
- Henley AB, Yang L, Chuang KL, Sahuri-Arisoylu M, Wu LH, Bligh SW, Bell JD. Withania somnifera Root Extract Enhances Chemotherapy through 'Priming'. PLoS One. 2017; 12(1): e0170917
- Schofield SE, Parkinson JR, Henley AB, Sahuri-Arisoylu M, Sanchez-Canon GJ, Bell JD. Metabolic dysfunction following weight cycling in male mice. Int J Obes (Lond). 2017; 41(3): 402–411.