Research Centre for Optimal Health

About the centre

The Research Centre for Optimal Health (ReCOH) was established to deepen our understanding of the lifestyle-induced accelerated ageing process and to use this knowledge to deliver practical solutions to achieve optimal health throughout adult life.

Research groups associated with the Research Centre for Optimal Health include the Cancer Mechanisms and Biomarkers research group, the Genomics and Infectious Diseases research group, the Health Data Science research group and the Medicines Diagnostics and Disease Modelling research group.

More about the research centre

Publications

Our most recent publications include:

O'Donovan SD, Rundle M, Thomas EL, Bell JD, Frost G, Jacobs DM, Wanders A, de Vries R, Mariman ECM, van Baak MA, Sterkman L, Nieuwdorp M, Groen AK, Arts ICW, van Riel NAW, Afman LA. Quantifying the effect of nutritional interventions on metabolic resilience using personalized computational models. iScience. 2024 Feb 29;27(4):109362. doi: 10.1016/j.isci.2024.109362
Smith HE, Mackenzie AM, Seddon C, Mould R, Kalampouka I, Malakar P, Needham SR, Beis K, Bell JD, Nunn A, Botchway SW. The use of NADH anisotropy to investigate mitochondrial cristae alignment. Sci Rep. 2024 Mar 12;14(1):5980. doi: 10.1038/s41598-024-55780-5. PMID: 38472304; PMCID: PMC10933486
Mould RR, Mackenzie AM, Kalampouka I, Nunn AVW, Thomas EL, Bell JD, Botchway SW. Ultra weak photon emission-a brief review. Front Physiol. 2024 Feb 14;15:1348915. doi: 10.3389/fphys.2024.1348915
Thanaj M, Basty N, Whitcher B, Sorokin E, Liu Y, Srinivasan R, Cule M, Thomas EL, and Bell JD. Precision MRI phenotyping of muscle volume and quality at a population scale. Front. Physiol., 15, 1288657 (2024). https://doi.org/10.3389/fphys.2024.1288657
Thanaj M, Basty N, Cule M, Sorokin EP, Whitcher B, Bell JD and Thomas EL. Liver shape analysis using statistical parametric maps at population scale. BMC Med Imaging 24, 15 (2024). https://doi.org/10.1186/s12880-023-01149-5

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