In order to advance treatment, promote health and prepare for future outbreaks, the group will focus on the generation and utilisation of (i) genetics, (ii) genomics, (iii) transcriptomics, (iv) proteomics (v) drug discovery and (vi) computational biology data and tools to:
- Understand the genetic changes and genetic conditions associated with infectious diseases.
- Understand the interactions between pathogen and host.
- Investigate the genes and pathways underlying pathogen virulence, biofilm formation, persistence of infections within the host as well as the pathogen adaptations to tolerate antimicrobial treatments.
- Identify biomarkers for the diagnosis of infectious diseases.
- Predict or infer antimicrobial resistance.
- Drive the screening and development of novel antimicrobial compounds to treat infectious diseases.
- Study the genomic diversity of microbial agents infecting humans, to determine factors associated with epidemiologically-prevalent lineages and propose actions to prevent the dissemination of infections within the population.
- Investigate the diversity, evolution and molecular ecology of arthropod disease vectors and the parasites and pathogens they transmit.
For more information on current projects, visit our Ongoing Research Projects page.