Publications

To view our latest publications, visit the Cancer Mechanisms and Biomarkers page on WestminsterResearch.

Cancer Mechanisms and Biomarkers' recent publications include:

• Dirimtekin E, Mortoglou M, Alavanda C, Benomar Yemlahi A, Arslan Ates E, Guney I and Uysal-Onganer P. (2023).  miR-34a-FOXP1 loop in Ovarian Cancer. ACS Omega, Jul 18;8(30):27743-27750. doi: 10.1021/acsomega.3c03867.eCollection 2023 Aug 1.
• Koushyar S, Uysal-Onganer P, Jiang W and Dart DA. (2023). Prohibitin links cell cycle, motility and invasion in Prostate Cancer cells. J. Mol. Sci. 2023 Jun 8;24(12):9919. doi: 10.3390/ijms24129919
• Edwards K, Lydyard PM, Kulikova N, Tsertsvadze T, Volpi EV, Chiorazzi N, Porakishvili N. The role of CD180 in hematological malignancies and inflammatory disorders. Mol Med. 2023 Jul 17;29(1):97. doi: 10.1186/s10020-023-00682-x. PMID: 37460961; PMCID: PMC10353253.
• Obakan Yerlikaya P, Arisan ED, Mehdizadehtapeh L, Uysal-Onganer P, Coker Gurkan A. (2023). The use of plant steroids in COVID-19 treatment: Current status and future perspectives. Eur J of Biol–Advance Online Publication. DOI:10.26650/EurJBiol.2023.1130357 
• Mortoglou M, Mirales F, Mould RR, Sengupta D and  Uysal-Onganer P. (2023). Inhibiting CDK4/6 in Pancreatic Ductal Adenocarcinoma via microRNA-21. Eur J of Cell Biol-2023 Apr 25;102(2):151318. doi: 10.1016/j.ejcb.2023.151318. Epub ahead of print. PMID: 37105116.
• Borna M, Woloshynowych M, Schiano-Phan R, Volpi EV, Usman M. A correlational analysis of COVID-19 incidence and mortality and urban determinants of vitamin D status across the London boroughs. Sci Rep. 2022 Jul 11;12(1):11741. doi: 10.1038/s41598-022-15664-y. PMID: 35817805; PMCID: PMC9272647.
• Arisan S, Ozifliz Kilbas P, Rencuzogullari O, Coker Gurkan A, Obakan Yerlikaya P, Palavan N, Uysal-Onganer P, Arisan ED. (2022). Identification of serum circulating miR-100, miR-141, miR-145, miR-4463, and miR-653 expression profiles in prostate cancer and obesity patients.- Human Gene, 34,2022. https://doi.org/10.1016/j.humgen.2022.201109
• Arisan ED, Dart A, Grant GH, Dalby A, Kancagi D, Turan D, Yurtsever B, Karakus G, Ovali E, Lange S, and Uysal-Onganer P. (2022). miR-1307 is a significant target for SARS-CoV-2 infection in Vero cell models. ACS Omega, 2022 Oct 11;7(42):38003-38014. doi: 10.1021/acsomega.2c05245
• Tomar A, Uysal-Onganer P, Basnett P, Patti UK and Roy I (2022). Disease modeling of hard and soft cancer using PHA based 3D scaffolds- Cancers, 2022 Jul 21;14(14):3549. doi: 10.3390/cancers14143549.
• Manic L, Wallace D, Uysal-Onganer P, Taalah Y, Farooqi AA, Dukic-Cosic D, Bulat Z, Anotnijevic B, Buha-Dordevic A. (2022). Epigenetic mechanisms of metal carcinogenicity. Toxicology Reports, Vol 9, 778-787. 
• Fletcher D, Brown B, Javadala B, Uysal-Onganer P & Guinn B. (2022). miRNA expression in acute myeloid leukaemia: new targets for therapy? EJHaem. 2022 Apr 26;3(3):596-608. doi: 10.1002/jha2.441.
• Mortoglou M, Buha-Dordevic A, Dordevic V, Wallace D and Uysal-Onganer P (2022). Evaluation of the Nickel Exposure in Pancreatic Ductal Adenocarcinoma- Toxics 2022, 10, 148
• Mortoglou M, Miralles Arenas F, Arisan ED, Dart A, Jurcevic S, Lange S and Uysal- Onganer P, (2022). microRNA21 regulates stemness in Pancreatic Ductal Adenocarcinoma –Int. J. Mol. Sci. 2022, 23(3), 1275; https://doi.org/10.3390/ijms23031275. 
• Mortoglou M, Buha-Dordevic A, Dordevic V, Collins H, York L, Mani K, Val E, Wallace D and Uysal-Onganer P (2021). Role of microRNAs in response to Cadmium Chloride in Pancreatic Ductal Adenocarcinoma. Arch Toxicol. 2021 Dec 14. doi: 10.1007/s00204- 021-03196-9. 
• Ozifliz Kilbas P, Sonmez O, Coker Gurkan A, Obakan Yerlikaya P, Palavan N, Uysal- Onganer P, Arisan ED. (2021). In vitro investigations of the relationship between cholesterol metabolism and cancer via miR-33a in estrogen receptor targeting therapies in breast cancer cells. Cancers (Basel). 2021 Oct 23;13(21):5322. doi: 10.3390/cancers13215322 
• Jiggens E, Mortoglou M, Grant GH and Uysal-Onganer P (2021). The Applications and Roles of CDK4 in Pancreatic Cancer. Healthcare 2021, 9(11),1478 https://doi.org/10.3390/healthcare9111478
• Lanning B, Webber J, Uysal-Onganer P, Jian W, Clayton A, Dart A. (2021). Prostate Cancer Cell Extracellular Vesicles Increase Mineralisation of Bone Osteoblast Precursor Cells in an In Vitro Model. Biology. 10 (4), p. e318. doi.org/10.3390/biology10040318
• Mortoglou M, Tabin ZK, Arisan ED, Kocher HM, and Uysal Onganer P. (2021). Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy. Translational Oncology. 14 (7) 101090. https://doi.org/10.1016/j.tranon.2021.101090
• Mortoglou M, Wallace D, Djordjevic-Buha A, Djordjevic V, Arisan ED, Uysal-Onganer P. (2021). MicroRNAs Regulated Signaling Pathways: Potential Biomarkers for Pancreatic Ductal Adenocarcinoma. Stresses. 1 (1), pp. 30-47. doi.org/10.3390/stresses1010004
• Sevgin B, Coban MN, Coker Gurkan A, Obakan Yerlikaya P, Rencuzogullari O, Uysal-Onganer P, Arisan ED. (2021). Investigation of the effect of CDK4/6 inhibitors Palbociclib and Abemaciclib on PI3K / AKT/mTOR and AMPK-related signaling pathways in PANC-1 and MIA PaCa-2 pancreatic cancer cell lines. Stresses. 1 (1), pp. 48-68. doi.org/10.3390/stresses1010005
• Arisan ED, Recuzoglullari O, Cieza-Borrella C, Miralles Arenas F, Dwek M, Lange S and Uysal-Onganer P. (2021). miR-21 is required to sustain the epithelial-mesenchymal transition in metastatic breast cancer cells. Int J Mol Sci. 2021 Feb 4;22(4):1557. doi: 10.3390/ijms22041557. PMID: 33557112
• Uysal-Onganer P, D’Alessio S, Mortoglou M and Lange S. (2021). Peptidylarginine Deiminase Inhibitor Application, using Cl-amidine, PAD2, PAD3 and PAD4-isozyme Specific Inhibitors in Pancreatic Cancer Cells, reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. Int J Mol Sci. 2021 Jan 30;22(3):1396. doi: 10.3390/ijms22031396.
• Lange S, Arisan ED, Grant GH, Uysal-Onganer P. (2021). microRNAs for virus pathogenicity and host responses, identified in SARS-CoV-2 genomes, may play roles in viral-host co-evolution in putative zoonotic host species. Viruses. 2021 Jan 16;13(1):117. doi: 10.3390/v13010117.
• Bergsneider B, Bailey E, Ahmed Y, Gogineni N, Huntley D, Montano X. Analysis of SARS-CoV-2 infection associated cell entry proteins ACE2, CD147, PPIA, and PPIB in datasets from non SARS-CoV-2 infected neuroblastoma patients, as potential prognostic and infection biomarkers in neuroblastoma. Biochem Biophys Rep. 2021 Sep;27:101081. doi: 10.1016/j.bbrep.2021.101081. 
• Edwards K, Zaitseva K, Sayed U, Volpi EV, Nathwani A, Gribben JG, Lydyard P, Krysov S, Porakishvili N. Expression patterns of CD180 in the lymph nodes of patients with chronic lymphocytic leukaemia. Br J Haematol. 2021 Oct;195(2):e131-e134. doi: 10.1111/bjh.17680. Epub 2021 Jul 5. PMID: 34227107.
• Usman M, Woloshynowych M, Britto JC, Bilkevic I, Glassar B, Chapman S, Ford-Adams ME, Desai A, Bain M, Tewfik I, Volpi EV. Obesity, oxidative DNA damage and vitamin D as predictors of genomic instability in children and adolescents. Int J Obes (Lond). 2021 Sep;45(9):2095-2107. doi: 10.1038/s41366-021-00879-2. Epub 2021 Jun 22. PMID: 34158611; PMCID: PMC8380542.