- Genomics and Infectious Diseases
About me
Dr Manal Mohammed is a veterinary surgeon by training and she holds a PhD in Medical Microbiology from University of Liverpool. Manal is interested in investigating the effect of COVID-19 in accelerating the global threat of antibiotic resistance. Manal is also interested in understanding the complex dynamics of bacteria-phage interaction aiming to develop phage therapy for the treatment of antibiotic resistant bacteria. Manal's research interests also include application of next generation sequencing technologies and associated bioinformatics analyses tools in investigating the molecular basis of virulence of non typhoidal salmonellosis in humans.
Manal is very passionate about science communication, and has been interviewed by BBC Radio London, ITV News, BBC News, Daily Mail, METRO and The Independent newspapers. She also had the opportunity to present her research at the UK Parliament.
Teaching
Dr Manal Mohammed is a fellow at the Higher Education Academy. Manal teaches Microbiology, Medical Microbiology and Microbial Genomics across a wide range of undergraduate and postgraduate modules.
Award (27th April 2024): Dr Manal Mohammed wins Professional Excellence Award at G2T Global Awards https://www.westminster.ac.uk/news/dr-manal-mohammed-wins-profession...
Research
SELECTED PUBLICATIONS:
Mohammed, M.*, Casjens, S.R., Millard, A.D., Harrison, C., Gannon, L. and Chattaway, M.A. (2023). Genomic analysis of Anderson typing phages of Salmonella Typhimrium: towards understanding the basis of bacteria-phage interaction. Scientific Reports. 13 10484. https://doi.org/10.1038/s41598-023-37307-6
Manal Mohammed* & Beata Orzechowska (2021): Characterisation of phage susceptibility variation in Salmonella enterica Serovar Typhimurium DT104 and DT104b. MDPI Microorganisms 2021, 9(4), 865; https://doi.org/10.3390/microorganisms9040865.
Manal Mohammed* & Salina Thapa (2020): Evaluation of WGS-subtyping methods for epidemiological surveillance of foodborne salmonellosis. One Health Outlook. 2020 July 2:13. (https://www.westminster.ac.uk/news/student-salina-thapa-and-her-supe...).
Manal Mohammed*, Sabrina Cadel-Six, Marie-Leone Vignaud (2019): Whole-Genome Sequences of Two Salmonella enterica Serovar Dublin Strains That Harbor the viaA, viaB, and ompB Loci of the Vi Antigen. Microbiol Resour Announc. 2019 Apr 4;8(14).
Sabrina Cadel-Six, Marie-Leone Vignaud, Manal Mohammed* (2019): Draft Genome Sequence of Salmonella enterica subsp. enterica Serovar Dublin Strains from St. Nectaire and Morbier Cheeses Characterized by Multilocus Variable-Number Tandem-Repeat Analysis Profiles Associated with Two Fatal Outbreaks in France. Microbiol Resour Announc. 2019 Jan 3;8(1).
Manal Mohammed (2018): Old school wins: outbreak investigation of foodborne salmonellosis. Atlas of Science. http://atlasofscience.org/old-school-winsoutbreak-investigation-of-f...
Manal Mohammed (2018): Who fights whom? Understanding the Complex Dynamics of Bacteria-Phage Interaction using Anderson Phage Typing System. Journal of Infectious Diseases; Therapy, 6(3), 367.
Manal Mohammed (2017): Phage typing or CRISPR typing for epidemiological surveillance of Salmonella Typhimurium?. Biomed Central Research Notes 10(1): 578.
Manal Mohammed*, Simon Le Hello; Pimlapas Leekitcharoenphon; Rene Hendriksen (2017): The invasome of Salmonella Dublin as revealed by whole genome sequencing. BioMed Central Infectious Diseases 4;17(1):544.
This article has been republished in 2019 as a book chapter by Avid Science in the ebook (Top 5 Contributions on Infectious Diseses) http://www.avidscience.com/book/top-5-contributions-in-infectious-diseases/
Manal Mohammed* and Martin Cormican (2016): Whole Genome Sequencing Provides Insights into the Genetic Determinants of Invasiveness in Salmonella Dublin. Epidemiology and Infection 144(11):2430-2439.
Manal Mohammed* and Martin Cormican (2015): Whole genome sequencing provides possible explanations for the difference in phage susceptibility among two Salmonella Typhimurium phage types (DT8 and DT30) associated with a single foodborne outbreak. BioMed Central Research Notes 27;8:728.
Manal Mohammed*, Niall DeLappe, Jean O’Connor, Paul McKeown, Patricia Garvey and Martin Cormican (2015): Whole genome sequencing provides an unambiguous link between Salmonella Dublin outbreak strain and a historical isolate. Epidemiology and Infection 13:1-6.
Anne Marie Burns, Peadar G. Lawlor, Gillian E. Gardiner, Evonne M. McCabe, Des Walsh, Manal Mohammed, Jim Grant and Geraldine Duffy (2015): Salmonella occurrence and Enterobacteriaceae counts in pig feed ingredients and compound feed from feed mills in Ireland. Preventive Veterinary Medicine 121 (3-4):231-239.
BOOK CHAPTER:
Beata Orzechowska and Manal Mohammed* (2019): The War between Bacteria and Bacteriophages. (https://www.westminster.ac.uk/news/biomedical-science-student-and-he...).
SELECTED PRESENTATIONS:
Manal Mohammed: (4 June 2024): “Fighting superbugs with a powerful green weapon” - invited talk at the Annual Sustainable Development Goal workshop, University of Westminster, UK.
Manal Mohammed & Rasha El Mahdy (8-11 April 2024): Genomic Analysis of uropathogenic E. coli strains in Egypt. Microbiology Society Annual Conference 2024 in Edinburgh, UK.
Manal Mohammed (20-21 March 2024): Developing Phage Therapy by Investigating the Basis of Bacteria-Phage interaction. ELRIG UK, Manchester.
Manal Mohammed (10 October 2023): Investigating the Dynamics of Host-Phage interaction: Towards Effective Phage Therapy. (Keynote Speaker) 5th International Conference on Applied Microbiology and Beneficial Microbes, London https://crgconferences.com/appliedmicrobiology/2023/
Manal Mohammed, Mkpouto Monday Otong, Clement Mboto, Ben Solomon Asuquo, Bernard Okoro, Christopher Ekpo, Uwem Edet Okon, Elizabeth Nkagafel Mbim (17 April 2023): Genomic Analysis of Clinical Multi-drug Resistant E. coli in Nigerian Hospitals. Annual Microbiology Conference. Birmingham 17-20 April 2023.
Manal Mohammed (4-5 October 2022): Genetic basis of phage-host interaction: Towards effective phage therapy of invasive non-typhoidal Salmonella. Research&Innovation ELRIG. London.
DRUG DISCOVERY 2022: DRIVING THE NEXT LIFE SCIENCE REVOLUTION
Manal Mohammed (31 August 2022): Non-typhoidal SalmonellaDublin: Why should we all care?. International Colloquium on Infectious Diseases, Epidemiology and Public Health (ICIEP 2022), Amsterdam (invited speaker and organising comittee member).
Manal Mohammed; Beata Orzechowska: Investigating the difference in phage susceptibility among MDR Salmonella Typhimurium phage types DT104 and DT104b. E-poster presentation (Microbiology Annual Conference, 26-30 April 2021).
Salina Thapa & Manal Mohammed (1 October 2019): Breaking the wall of Salmonella outbreaks investigation. Falling Walls Lab, London, UK.
Manal Mohammed, Sabrina Cadel-Six, Marie-Leone Vignaud, Myron M. Levine (8-11 April 2019): Characterization of the Mobilome of Invasive Non-typhoidal Salmonella Dublin. The Microbiology Society Annual Conference. ICC Belfast, UK. (Dr Mohammed was invited by the Microbiology Society to co-chair the Virology Workshop: Pathogenesis on 10th April).
Salina Thapa and Manal Mohammed (8-11 April 2019): Characterisation of Prophages in Salmonella Typhimurium DT8. The Microbiology Society Annual Conference. ICC Belfast, UK.
Manal Mohammed (2-3 April 2019): Novel Approaches for Treatment and Prevention of Invasive Non-typhoidal Salmonella. Research&Innovation ELRIG. Cambridge, UK.
Manal Mohammed (1-2 November 2018): Novel Insights Into the prevention and Treatment of Invasive SalmonellaDublin. Invited speaker and congress moderator at the 7th European Clinical Microbiology congress. London, UK.
Manal Mohammed (14-16 June 2018): Towards Treatment and Prevention of Invasive Non-typhoidal Salmonella. Keynote Speech at the International Conference on Advanced Microbiology and Education. London, UK.
Manal Mohammed, Simon Le Hello; Pimlapas Leekitcharoenphon; Rene Hendriksen (22-25 April 2017): Whole-genome sequencing reveals the secrets of the Salmonella Dublin invasome. European Society of Clinical Microbiology and Infectious Diseases (ECCMID) in Vienna, Austria.
Manal Mohammed and Martin Cormican (17-19 June 2015): Bacteriophage therapy: a promising alternative to evade bacterial resistance to antibiotics. Society of General Microbiology (SGM) Irish branch meeting 2015 at National University of Ireland Galway, Ireland.
Manal Mohammed and Martin Cormican (17-19 June 2015): Microbial Whole Genome Sequencing Revolutionizing the Way We Investigate Foodborne Outbreaks. Society of General Microbiology (SGM) Irish branch meeting 2015 at National University of Ireland Galway, Ireland.
Manal Mohammed and Martin Cormican (17-19 June 2015): Comparative Genomics Reveals the Genetic Basis of Invasiveness in Salmonella enterica serovar Dublin. Society of General Microbiology (SGM) Irish branch meeting 2015 at National University of Ireland Galway, Ireland.
Manal Mohammed and Martin Cormican: Genomic Correlates of Failure of Aes Laboratorie Salmonella Agar Plate to Detect Salmonella Dublin. Society of General Microbiology (SGM) Irish branch meeting 2015 at National University of Ireland Galway, Ireland.
Manal Mohammed, Niall DeLappe, Jean O’Connor, Paul McKeown, Patricia Garvey and Martin Cormican (25-28 April 2015): Rapid Whole-Genome Sequencing for Investigation of a Salmonella Dublin Gastroenteritis Outbreak in Ireland. European Society of Clinical Microbiology and Infectious Diseases (ECCMID) in Copenhagen, Denmark on 25 – 28 April 2015.
Manal Mohammed and Martin Cormican (4 October 2014): Microbial Whole Genome Sequencing Reveals the Genetic Basis of Virulence and Host Adaptation in Salmonella Dublin and Proves to be a Powerful Laboratory Method for Investigating Foodborne Outbreaks. Irish Society of Clinical Microbiologists Autumn meeting 2014 at Davenport Hotel, Dublin 2, Ireland. Awarded First Prize in the Rapid Fire Poster Presentations Competition, sponsored by MSD Pharmaceuticals.
Manal Mohammed and Martin Cormican (21 August 2014): Toward Investigating the Molecular Basis of Salmonella Typhimurium Phage Typing with Whole Genome Sequencing. Society of General Microbiology (SGM) Irish branch summer meeting 2014 (at University of Limerick, Ireland)- Awarded First Prize in the Poster Presentations Competition, sponsored by Science Foundation Ireland (SFI).
Manal Mohammed, Siritorn Butrapet, Sareen E. Galbraith, Ichiro Kurane, Alan Radford and Tom Solomon (27th April 2010): Molecular Evolution of Japanese Encephalitis Virus, University of liverpool, School of Infection and Host Defence Away Day, Ness Botanic Gardens Neston, Wirral. Awarded second prize in the Poster Presentations Competition.
Manal Mohammed, Siritorn Butrapet, Sareen E. Galbraith, Ichiro Kurane, Alan Radford and Tom Solomon (31st March 2010): Molecular phylogenetic and evolutionary analyses of Muar strain of Japanese encephalitis virus: the missing 5th genotype. Society of General Microbiology (SGM) Spring 2010 Meeting, Edinburgh International Conference Centre.
Manal Mohammed, Siritorn Butrapet, TomohikoTakasaki, Ichiro Kurane, Sareen Galbraith and Tom Solomon (1st April 2009): Phylogenetic analysis of Muar strain of Japanese encephalitis virus reveals a possible 5th Genotype, Society of General Microbiology (SGM) Spring 2009 Meeting, Harrogate International Centre.
Publications
For details of all my research outputs, visit my WestminsterResearch profile.