About the group
The Pathobiology and Extracellular Vesicles research group, within the Research Centre for Resilience, is based in the University of Westminster's School of Life Sciences. The research group aims to unravel the interplay of innate, adaptive, and epigenetic contribution to pathobiological processes, leading to the identification of novel molecular targets and therapies to improve human health during their lifespan and to expand our understanding of the One Health concept.
Projects and initiatives
Find out about the funded projects undertaken by the Pathobiology and Extracellular Vesicles research group
Publications
Pathobiology and Extracellular Vesicles' recent publications include:
- Wu X, Cunningham KP, Bruening-Wright A, Pandey S, Larsson HP (2024). Loose Coupling between the Voltage Sensor and the Activation Gate in Mammalian HCN Channels Suggests a Gating Mechanism. Int J Mol Sci. 2024; 25(8):4309. https://doi.org/10.3390/ijms25084309
- Welsh JA, Goberdhan DCI, O'Driscoll L, et al…MISEV Consortium, Théry C, Witwer KW. (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles. 2024;13(2):e12404. doi:10.1002/jev2.12404
- Mitra S, Harvey-Jones K, Kraev I, Verma V, Meehan C, Mintoft A, Norris G, Campbell E, Tucker K, Robertson NJ, Hristova M, Lange S (2023). The Extracellular Vesicle Citrullinome and Signature in a Piglet Model of Neonatal Seizures. Int J Mol Sci.24(14):11529.
- Coates CJ, Kraev I, Rowley AF, Lange S (2023). Extracellular vesicle signatures and protein citrullination are modified in shore crabs (Carcinus maenas) infected with Hematodinium sp. Virulence. 14(1):2180932.
- Jorfi S, Ansa-Addo EA, Mariniello K, Warde P, bin Senian AA, Stratton D, Bax BE, Levene M, Lange S, Inal JM (2023). A Coxsackievirus B1-mediated nonlytic Extracellular Vesicle-to-cell mechanism of virus transmission and its possible control through modulation of EV release. Journal of General Virology. In press.